Leadership & Program Management
Director, Stable and Medical Isotope Program
The Director of the Stable and Medical Isotope Program will lead the technical execution, research, and industrialization of LIST’s isotope enrichment initiatives. This role requires deep expertise in lasers, spectroscopy, and enrichment processes, coupled with strong leadership skills to translate advanced laboratory demonstrations into reliable, scalable systems.
The Director will be responsible for designing and implementing technical maturation roadmaps (from TRL 4–7), ensuring robust experimental execution, advancing laser-isotope enrichment capabilities, and managing cross-disciplinary teams of engineers and scientists. While knowledge of stable and medical isotope applications (radiopharmaceuticals, diagnostics, therapy) is highly valued, the primary emphasis is on laser-based spectroscopy, isotope separation physics, and the engineering execution of enrichment technologies.
Full Time
Location – Southeast
Director, Stable and Medical Isotope Program
Key Responsibilities
- Technical Leadership: Drive technical execution of LIST’s Stable and Medical Isotope Program, focusing on laser-based enrichment, spectroscopy, and experimental validation.
- Laser & Spectroscopy Development: Lead development, optimization, and scaling of advanced laser systems for isotope separation, ensuring integration with LIST’s CRISLA™ platform.
- Experimental Execution: Direct laboratory testing, pilot demonstrations, and process engineering to advance isotope separation from concept through industrial readiness.
- Technology Roadmapping: Develop and implement TRL progression strategies, ensuring readiness for commercial deployment.
- Team Building: Recruit, mentor, and manage a multidisciplinary technical team (laser scientists, optical engineers, chemists, process engineers).
- Cross-Functional Integration: Coordinate with regulatory, commercial, and medical stakeholders while maintaining a strong technical execution focus.
- Partnerships: Establish collaborations with DOE national labs, universities, hospitals, and commercial partners to accelerate development and adoption.
- Delivery: Ensure enrichment technology milestones are met on schedule, within budget, and aligned with LIST’s intellectual property and commercialization goals.
Qualifications
- Ph.D. or M.S. in Physics, Physical Chemistry, Laser/Optical Engineering, or related field.
- 10+ years of experience in laser development, spectroscopy, optical systems, or isotope enrichment technologies.
- Proven record of leading technical teams in experimental programs from lab to pilot to industrial scale.
- Demonstrated expertise in laser-based spectroscopy and its application to isotope separation or related advanced materials processing.
- Strong engineering background with ability to oversee experimental execution, diagnostics, and systems integration.
- U.S. citizenship required; ability to obtain DOE/NRC Q-clearance preferred.
Highly Preferred
- Experience in isotope enrichment, nuclear technology, radiopharmaceuticals, or medical isotope supply chains (e.g., Mo-99, Cu-67, Ac-225, Lu-177).
- Familiarity with nuclear regulatory frameworks (DOE, NRC, FDA).
- Understanding of TRL progression and commercialization pathways.
- Strong communication skills to engage technical and non-technical stakeholders.
- Entrepreneurial mindset, able to thrive in a fast-paced, technically demanding environment.
Benefits
- Competitive executive-level salary and performance-based incentives.
- Equity participation in LIS Technologies Inc.
- Comprehensive health, dental, and vision insurance.
- Relocation support (if applicable).
- Monday to Friday, on-site 5 days a week.
- Opportunity to lead a laser-driven isotope enrichment program shaping the future of U.S. isotope supply chains.
Complete the Application Form Below:
Director of Human Resources
This is a full-time on-site role in our gorgeous newly renovated facility for a Director of Human Resources located in Oak Ridge, Tennessee. For the right candidate we are open to relocation. The Director of Human Resources will oversee HR policies, manage employee relations, ensure compliance with labor and employment laws, and handle performance management. The role involves developing and implementing HR strategies, supporting employee development, and fostering a positive workplace culture.
Full Time
Location – Southeast
Director of Human Resources
Qualifications
- Strong knowledge of Human Resources (HR) and HR Policies
- Experience in Employee Relations and Performance Management
- Thorough understanding of Labor and Employment Law
- Excellent communication and leadership skills
- Ability to work collaboratively in a team and manage tasks independently
- Bachelor’s degree in Human Resources, Business Administration, or related field; advanced degree is a plus
- Professional HR certification (e.g., SHRM-CP, PHR) is preferred
Complete the Application Form Below:
Quality & Compliance
Quality Assurance Manager
We are looking for an experienced Quality Assurance Manager to implement the Laser Isotope Separation Technologies (L.I.S.T.) quality assurance program as we develop production scale enrichment processes based on our patented Laser Isotope Separation Technology process. The L.I.S.T. process has many advantages, being the only USA-origin and patented laser uranium enrichment company, and several major advantages over traditional methods such as gas diffusion, and centrifuges. The position reports to the L.I.S.T. President and will be based in our Oak Ridge, Tennessee office. You’ll work independently applying your knowledge to projects and processes. This is a fantastic opportunity to make a significant impact in a growing industry, collaborate with talented professionals, and grow your career in a supportive and innovative environment.
Full Time
Location – Southeast
Salary: $150,000 – $180,000
Quality Assurance Manager
Key Responsibilities
- Quality oversight to ensure work is performed in strict accordance with requirements of the quality assurance program and supporting procedures, work-instructions, and forms.
- Ensure compliance with environmental, safety, and health program requirements.
- Collaborate with the production team to implement quality improvements and perform causal analysis investigations on project-related issues.
- Assists technical staff with the creation of quality plans and acceptance criteria lists, and selection of hold points on vendors’ manufacturing inspection plans.
- Quality oversight to support supplier qualification and verification activities to ensure work is performed in strict accordance with requirements.
- Maintain the List of Approved/Qualified Suppliers.
- Promote Continuous Improvement and the timely reporting of all conditions that affect Quality.
- Lead and mentor personnel to ensure the correct behaviors are developed and reinforced.
- May perform other duties as assigned.
Qualifications
- Bachelor’s degree in engineering or a related field. Experience may be considered in lieu of degree.
- 5 years of experience in quality assurance, with 2 years nuclear quality experience in a Department of Energy (DOE), Nuclear Regulatory Commission (NRC), or similar environment.
- Knowledge of Quality standards such as ISO 9001, ASME NQA-1, and ASME III.
- Current Lead Auditor Certification.
- Experience with Software QA in accordance with NQA-1-2022, Part II, Subpart 2.7.
- Excellent verbal and written communication skills.
- Ability to work and demonstrate critical thinking individually and as part of a diverse team.
- Ability to function well in a fast-paced environment, set priorities to accomplish multiple tasks within deadlines, and adapt to ever changing needs.
- A team player with effective communication and a strong sense of responsibility.
Preferred Qualifications
- Experience with uranium fuel production and enrichment.
- Experience with commercial grade dedication.
- Previous certification in non-destructive examination.
Special Requirements
- Q Clearance: This position requires the ability to obtain and maintain a clearance from the Department of Energy. As such, this position requires passing a background check and a pre-placement drug test and participation in an ongoing random drug testing program.
- This position requires access to radiologically controlled areas. Ability to meet all safety requirements is mandatory.
- Business travel to support supplier surveys and/or company audits.
Benefits
This role offers an exciting opportunity to contribute to the forefront of laser technology development, driving innovations that shape the future of laser enrichment in the industry.
- Attractive salary $150-180k depending on level of experience.
- Comprehensive medical, dental, and vision benefits.
- Full-time, on-site 5 days a week in Oak Ridge, TN.
- Relocation support may be provided (if applicable).
Complete the Application Form Below:
Engineering & Technical
Mechanical Engineering Specialist - Gas Separator and Jet Design
This role focuses on mechanical design and engineering of gas separator systems, jet assemblies, and high-precision flow structures. The successful candidate will develop mechanical concepts, build 3D models, specify materials, and lead fabrication from prototype to production. The engineer will collaborate closely with laser, process, and manufacturing teams to deliver hardware that supports CRISLA gas-phase separation technology.
Full Time
Location – Southeast
Salary: $150,000 – $180,000
Mechanical Engineering Specialist - Gas Separator and Jet Design
Key Responsibilities
- Lead the design and development of gas separation assemblies and flow manifolds for isotope enrichment systems.
- Generate and manage detailed 3D CAD models and manufacturing drawings.
- Develop adiabatic expansion configurations optimized for molecular flow uniformity, meeting system objectives.
- Specify materials, tolerances, and sealing solutions suitable for high-vacuum corrosive/high-temperature environments.
- Work with vendors to support machining and precision assembly of components.
- Perform basic analytical modeling (mass flow, Reynolds number, expansion ratios) to support mechanical design choices.
- Conduct design reviews and lead prototype build iterations with cross-functional teams.
- Ensure nuclear-grade mechanical integrity and adherence to safety, quality, and performance standards.
- Support experimental test setup, assembly, and mechanical integration in lab environments.
- Produce engineering reports, specifications, and presentations for internal and external stakeholders.
Minimum Qualifications
- Professional Degree(PhD/MSc). in Mechanical Engineering, Aerospace Engineering, or related field.
- 10+ years in mechanical design and engineering, ideally in high-vacuum or gas-dynamic systems.
- Advanced proficiency with SolidWorks, Inventor, or equivalent 3D CAD software.
- Experience with machined components, tolerancing (GD&T), and build-for-manufacture design practices.
- Experience designing and hands on experience with entire assemblies.
- Strong understanding of gas expansion, pressure regulation, and thermal-mechanical coupling.
- Excellent written communication and technical documentation skills.
- U.S. citizenship and ability to obtain and maintain a DOE Q-clearance.
Preferred Experience
- Demonstrated expertise in precision nozzle and separator design, or related high-velocity flow hardware.
- Experience designing mechanisms.
- Experience designing dynamic seals.
- Experience with supersonic or molecular beam systems, vacuum manifolds, or separator jet design.
- Demonstrated expertise in adiabatic expansion systems or related high-velocity flow hardware.
- Knowledge of gas transport phenomena, thermal gradients, and flow-stabilizing design.
- Familiarity with laser interaction hardware, precision optical alignment, and cryogenic or heated assemblies.
- Exposure to nuclear, aerospace, or semiconductor hardware environments.
- Experience managing prototype-to-production transition
Compensation & Benefits
- Salary: $150,000–$180,000 (commensurate with experience)
- Equity: Competitive stock-option package
- Benefits: Full medical, dental, and vision
- Relocation: Assistance available for Oak Ridge, TN
Complete the Application Form Below:
Optical Design Engineer
The Optical Design Engineer will lead the development, optimization, and implementation of optical systems used for our cutting-edge infrared gas laser systems that are primarily used for isotope enrichment. This role requires a deep understanding of optical engineering principles in relation to laser physics. The ideal candidate will have a proven track record in designing high-performance optics/laser systems and a strong ability to translate innovative concepts into scalable, reliable solutions. The position requires the ability to simulate the propagation of free-space laser beams, and the optics and opto-mechanics required to shape the beam caustics and beam profile. Hands-on experience in the lab for the integration/implementation of the optical system is highly desired.
Full Time
Location – Southeast
Salary: $150,000 – $180,000
Optical Design Engineer
Key Responsibilities and Areas of Expertise
- Expertise in ray tracing & POP modeling using Zemax, FRED, etc
- Design of stable laser resonators, how it impacts laser beam quality and beam caustics in free space propagation
- Mechanical & thermal stability of the laser resonator, and how it impacts laser performance
- Knowledge of opto-mechanical systems used for specific optical components
- Experience/knowledge with dispersive resonators (i.e. grating) for wavelength adjustment
- Experience/knowledge with lenses & telescopes (i.e. spherical, OAP, etc.) – reflective vs refractive
- Experience/knowledge with other optics, i.e. Brewster windows, output couplers, beam splitters, adaptive optics, phase-conjugated mirrors, etc.
- Solid understanding of polarized laser beams, and how to control it
- Experience/knowledge of optics associated for laser metrology
- Perform qualification testing, user guide and other technical documents.
- Solid vendor knowledge of optics and coatings manufacturers’
- Draft and maintain design documentations including BOM, procedures and tests
- Knowledgeable with Laser Induced Damage, LIDT of optics & coatings.
Qualifications
- Majored in Optics, Physics. Master’s degree with 5 or more years of work experience. Bachelor degree with 10 or more years of work experience.
- Demonstrated solid understanding and depth knowledge in optics/laser theory and optical engineering. Proficient with Optical Design Software (CodeV/Zemax/TracePro/Fred)
- Hands-on experience with laser alignment, optical metrology, and diagnostics.
- Familiarity with basic principles of lasers and laser system design
- A team player with effective communication and a strong sense of responsibility.
Highly Preferred
- A background in high-power laser optics, infrared optics, Plasma physics or Optomechanical design is highly desirable
- Knowledge of advanced gas laser applications in industrial, medical, or research fields.
- Familiarity with high-voltage systems and gas handling techniques.
- Experience in thermal management and mechanical integration for laser systems.
- Project management skills and the ability to work in cross-disciplinary teams.
- Excellent written and verbal communication skills for technical reporting and collaboration.
This role offers an exciting opportunity to contribute to the forefront of laser technology development, driving innovations that shape the future of laser enrichment in the industry.
Benefits
- Attractive salary $150k – $180k, depending on level of experience.
- Stock options available for the right candidate.
- Comprehensive medical, dental, and vision benefits.
- Monday to Friday, on-site 5 days a week.
- Relocation support may be provided (if applicable).
Complete the Application Form Below:
Laser Engineer / Technician
The Laser Technician will work hands-on in the laboratory to support the development, testing, and maintenance of advanced infrared gas laser systems used in isotope enrichment. This role emphasizes practical, in-lab work such as system assembly, alignment, calibration, troubleshooting, and safety compliance. The ideal candidate enjoys working directly with lasers and optical systems and has a strong foundation in laser technology and laboratory practices.
Full Time
Location – Southeast
Salary: $80,000 – $120,000
Laser Engineer / Technician
Key Responsibilities
- Assist in the installation, alignment, calibration, and maintenance of infrared gas laser systems
- Conduct system performance tests, collect data, and assist in troubleshooting laser and sub-system issues
- Support experimental setups and contribute to ongoing laser development and optimization projects
- Perform optical metrology and diagnostics under supervision of senior staff
- Ensure compliance with laser safety protocols and laboratory procedures
- Document laboratory activities and results clearly and accurately
- Collaborate with engineering, R&D, and operations teams to achieve technical objectives
Required Skills and Qualifications
- Hands-on experience with lasers, optics, or related technical systems (academic or industrial)
- Familiarity with basic laser principles, alignment techniques, and optical diagnostics
- Strong mechanical and problem-solving skills for laboratory work
- Team-oriented with effective communication and responsibility
- Associate’s or bachelor’s degree in physics, electrical engineering, optical engineering, or related technical field (or equivalent lab experience)
- 5+ years of practical experience working in a laboratory with lasers, optics, or precision equipment preferred
Benefits
- Attractive salary $80-120k/year, depending on level of experience
- Comprehensive medical, dental, and vision benefits.
- Monday to Friday, on-site 5 days a week.
- Relocation support may be provided (if applicable).
Complete the Application Form Below: